The urinary metabolome of healthy newborns
WebFeb 27, 2015 · The newborns’ metabolic profiles were acquired using liquid chromatography coupled to mass spectrometry. The data showed that meconium and urine metabolome patterns clearly discriminated GDM cases from controls. Fourteen meconium metabolic biomarkers and three urinary metabolic biomarkers were tentatively identified for GDM. WebNov 1, 2015 · The aim of this study was to provide normative values for the urinary steroid metabolome of healthy newborns at short time intervals in the first year of life. Methods We conducted a prospective, longitudinal study to measure 67 urinary steroid metabolites in 21 male and 22 female term healthy newborn infants at 13 time-points from week 1 to ...
The urinary metabolome of healthy newborns
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WebNoninvasive monitoring of evolving urinary metabolic patterns in neonatal encephalopathy Noninvasive monitoring of evolving urinary metabolic patterns in neonatal encephalopathy . 2024 May 5. doi: 10.1038/s41390-021-01553-z. Authors WebJun 16, 2024 · The researchers measured the concentrations of nearly 140 chemicals in urine samples from 48 healthy, full-term newborn babies in the first hours after their birth. The results quantified 86...
WebSep 4, 2013 · As a biological waste material, urine typically contains metabolic breakdown products from a wide range of foods, drinks, drugs, environmental contaminants, endogenous waste metabolites and bacterial by-products. Many of these compounds are … WebRecently, the number of women suffering from gestational diabetes mellitus (GDM) has risen dramatically. GDM attracts increasing attention due to its potential harm to the heath of both the fetus and the mother. We designed this case–control study to investigate the …
WebTargeted tandem mass spectrometry (MS/MS)-based metabolomic assays were used to identify and quantify 136 metabolites of biomedical interest in the urine from 48 healthy, full-term term neonates, collected in the first 24 h of life. The knowledge of normal metabolite … WebMay 20, 2024 · A high-quality urinary metabolome for children of all ages is in great demand for investigating the metabolic changes in healthy children at each stage throughout early childhood, characterizing early-life physical and environmental exposures and assessing their general health status. ... The urinary metabolome of healthy newborns. Metabolites ...
WebWe hypothesize that the urinary metabolome of newborns with NE reflects the evolution of injury patterns observed with magnetic resonance imaging (MRI). METHODS: Eligible patients were...
WebApr 4, 2024 · The Urinary Metabolome of Healthy Newborns. Metabolites 2024-04 Journal article Author. DOI: 10.3390/metabo10040165 Contributors: Yamile ... bunking bed - chapter 27Web1. INTRODUCTION. The Developmental Origin of Health and Disease (DOHaD), or the foetal programming of future health, is widely accepted by the scientific community. 1 This hypothesis implies that every event that happens during the perinatal period may affect the health status of an individual up to their adult life. Several factors can affect the trajectory … bunkin county ncWebFeb 22, 2024 · Most metabolites of steroid hormone biosynthesis were upregulated in the urinary metabolome in healthy controls with pregnancy. ... resistance with the maternal metabolome and newborn outcomes. ... halifax newport isle of wightWebOct 22, 2024 · In this study, the urinary metabolome of babies born to GDM mothers was characterized. In total, 144 neonatal and maternal (second and third trimesters of pregnancy) urinary samples were analyzed using targeted metabolomics, combining … bun kinetic meaningWebThe Urinary Metabolome of Healthy Newborns CLAUDIA RAQUEL DIAZ CASTILLO 2024, Metabolites Abstract The knowledge of normal metabolite values for neonates is key to establishing robust cut-off values to diagnose diseases, to predict the occurrence of new … halifax newport isle of wight opening timesWeb1 day ago · Background: Dietary (poly)phenol consumption is inversely associated with cardiovascular disease (CVD) risk in epidemiological studies, but little is known about the role of the gut microbiome in this relationship. Methods: In 200 healthy females, aged … halifax newport iwWebMay 5, 2024 · The urinary metabolome of newborns with NE was studied employing three complementary analytical methods, i.e., untargeted UPLC–QTOFMS, semi-targeted CE–TOFMS, and a targeted method for the... bunking fanning school