2024 The integron: adaptation on demand

The integron: adaptation on demand

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August undefined, 2024

WebFeb 7, 2024 · Integrons are bacterial genetic elements notorious for their role in spreading antibiotic resistance in clinical settings. In the natural environment, integrons present a … WebJan 20, 2024 · The well-balanced mechanism of integron expression is intricately related with environmental signals, host cell physiology, fitness, and survival, ultimately leading to …

The SOS Response Controls Integron Recombination

WebMay 22, 2009 · Integrons are found in the genome of hundreds of environmental bacteria but are mainly known for their role in the capture and spread of antibiotic resistance determinants among Gram-negative pathogens. We report a direct link between this system and the ubiquitous SOS response. Webjournals.asm.org healthiest stainless steel cookware

Methods for the targeted sequencing and analysis of integrons …

WebMar 17, 2024 · Integrons are microbial genetic elements that can integrate mobile gene cassettes. They are mostly known for spreading antibiotic resistance cassettes among human pathogens. However, beyond clinical settings, gene cassettes encode an extraordinarily diverse range of functions important for bacterial adaptation. The recovery … WebJan 28, 2024 · The relationship between class 1 integron carriage and the concentration of five trace elements and heavy metals was also investigated, finding no significant association. ... Mazel D. The integron: adaptation on demand. In: Sandmeyer S, editor. Mobile DNA III. Washinton, DC: ASM Press; 2015. p. 139–61. 48. WebApr 7, 2024 · Competition experiments between resistant bacteria carrying the integron and susceptible strain lacking the integron were performed in the presence of various … healthiest starbucks drinks 2021

Gene cassettes and cassette arrays in mobile resistance integrons …

Integron activity accelerates the evolution of antibiotic

WebFeb 20, 2024 · Integron can capture and express antimicrobial resistance gene cassettes and plays important roles in horizontal gene transfer. The establishment of a complete in vitro reaction system will help to reveal integron integrase mediated site-specific recombination process and regulation mechanism. WebJun 3, 2009 · The discovery of integrons in the chromosome of many species has led to the identification of thousands of gene cassettes, mostly of unknown function, while integrons associated with transposons and plasmids carry mainly antibiotic resistance genes and constitute an important means of spreading resistance. healthiest starbucks drinks coldWebFeb 20, 2024 · Integron can capture and express antimicrobial resistance gene cassettes and plays important roles in horizontal gene transfer. The establishment of a complete in … good betting tips

"WebFeb 7, 2024 · Integrons are bacterial genetic elements notorious for their role in spreading antibiotic resistance in clinical settings. In the natural environment, integrons present a … " - The integron: adaptation on demand

The integron: adaptation on demand

Two-dimensional PCR for detecting class 1, 2 and 3 integrons

WebApr 29, 2024 · The ‘adaptation on demand’ model of the integron as an evolutionary catalyst assumes that antibiotic pressures impose strong selection for resistance cassettes to be positioned in first position, as we have reported for aadB. WebJun 15, 2016 · The Integron: Adaptation On Demand. Microbiology spectrum. 2015;3(2). View Article Google Scholar 10. Collis CM, Hall RM. Expression of antibiotic resistance genes in the integrated cassettes of integrons. Antimicrobial agents and chemotherapy. 1995;39(1):155–62.

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WebFeb 5, 2016 · We present a mathematical model of integron evolution within bacterial populations subject to fluctuating antibiotic exposures. Bacteria carrying a functional integrase that mediates reshuffling... WebThe integron is a powerful system which, by capturing, stockpiling, and rearranging new functions carried by gene encoding cassettes, confers upon bacteria a rapid adaptation …

WebApr 7, 2024 · The integron: adaptation on demand. Microbiol Spectr 3: MDNA3-0019-2014. PubMed Google Scholar Escudero JA, Loot C, Parissi V, Nivina A, Bouchier C, Mazel D . (2016). Unmasking the ancestral ... WebJul 24, 2024 · We decided that such a recombination system could be developed on the basis of the bacterial integron platform. Integrons play a major role in the dissemination of antibiotic resistance genes among clinically relevant Gram-negative pathogens ().The functionality of integrons relies on the activity of the integron integrase (hereafter …

WebFeb 7, 2024 · Integrons are genetic elements found in bacterial genomes. They have the ability to acquire, excise, rearrange, and express gene cassettes (Figure 1). Their potency has been substantiated due to their role in spreading antibiotic resistance in clinical settings, thereby mediating bacterial adaptation [1]. WebApr 6, 2024 · Integrons are genetic platforms that can capture and shuffle genes, thus providing instant adaptive benefits in fluctuating environments ( Stokes and Hall, 1989 ). …

WebMay 26, 2015 · Among elements reshaping bacterial genomes, integrons have a particularly important role in gene shuffling and allow the concentration of certain genes in compact …

WebApr 18, 2024 · Class 1 integrons structurally consist of three core elements: an integrase gene ( intI1 ), catalyzing site-specific recombination, a primary recombination site ( attI1) and a common promoter (Pc), enabling transcription of the gene cassettes. 6 Class 1 integrons play an important role in drug resistance gene transmission among bacteria … healthiest state in the nationWebNov 16, 2024 · Integrons are mostly known for their role in driving the global antibiotic resistance crisis by disseminating diverse resistance determinants among bacterial … healthiest starbucks espresso drinksWebMay 26, 2015 · The Integron: Adaptation On Demand (Pages: 139-161) José Antonio Escudero, Céline Loot, Aleksandra Nivina, Didier Mazel, Summary PDF References Request permissions CHAPTER 7 no Xer Site-Specific Recombination: Promoting Vertical and Horizontal Transmission of Genetic Information (Pages: 163-182) Caroline Midonet, … healthiest states 2021 healthiest state in usaWebFeb 26, 2024 · When bacteria encounter antibiotics, an enzyme called integrase is activated, allowing the organisms to shuffle the order of their cassettes in the integron. It is thought … healthiest starches to eatWebApr 29, 2024 · The ‘adaptation on demand’ model of the integron as an evolutionary catalyst assumes that antibiotic pressures impose strong selection for resistance cassettes to be … healthiest starbucks coffee drinksWebApr 1, 2015 · The integron is a powerful system which, by capturing, stockpiling, and rearranging new functions carried by gene encoding cassettes, confers upon bacteria a … healthiest state in usa 2022