Olfm4 and cancer
Web02. maj 2024. · Moreover, the cancer stem cell-like property of OLFM4 mediated by leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5), known as an intestinal stem … Web20. feb 2024. · 并且有文献指出，OLFM4在与富含亮氨酸重复序列G蛋白偶联受体5（leucinerich-repeat-containing G-protein-coupled receptor 5，Lgr5）关联的结肠癌干细胞中有表达[14-15]，而Lgr5与肿瘤的恶性程度直接相关，这也进一步证明了OLFM4与结肠癌肿瘤的分期相关，或许可将OLFM4 作为结肠癌 ...
Olfm4 and cancer
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WebProtein function (UniProt)i. Useful information about the protein provided by UniProt. May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leu kemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 ... Web18. jul 2024. · Cancer molecular subtyping (describing cancer subtypes) is important not least because of its potential relevance to choice of treatment [1,2].In the case of Colon Cancer, classifications of colorectal cancers (CRC) can be subdivided into 3–6 subtypes, based on gene expression profiles [1,2,3,4].Alternatively, CRC has been shown to divide …
Web01. mar 2007. · The results indicate that OLFM4 promotes proliferation of PANC‐1 cells by favoring transition from the S to G2/M phase and inhibition of small interfering RNA did not promote apoptosis. Induction of olfactomedin 4 (OLFM4GW112/hGC‐1) in cancer cells was recently reported to have a novel antiapoptotic action via binding to the potent apoptosis … Web24. mar 2024. · OLFM4 is secreted and may be detected in serum and plasma therefore representing a good candidate CRC marker as previously suggested for gastric cancer [35, 36]. Sec24C is an essential coat protein II (COPII) component and COPII is involved in protein transports from the endoplasmic reticulum (ER).
Web15. mar 2024. · Low expression of OLFM4 promoted lymph node and distant metastasis resulting in a poor prognosis of triple-negative breast cancer patients and low expression of OLFM4 in early gastric cancer was ... Web29. mar 2024. · circulating OLFM4 could be an interesting biomarker of early breast cancer. high expression of OLFM4 was involved in chemoresistance and was an independent …
Web21. mar 2024. · OLFM4 (Olfactomedin 4) is a Protein Coding gene. Diseases associated with OLFM4 include Atrophy Of Prostate and Colonic Benign Neoplasm.Among its related pathways are Innate Immune System and Adhesion.Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and cadherin binding.An …
postpartum stress syndrome treatmentWeb29. apr 2024. · These findings suggest that OLFM4 could be a useful marker for cancer precursors or early-stage CRC, and genetic manipulation of OLFM4 expression could be … postpartum support belt motherhood maternityWeb10. jan 2024. · Chemoresistance was observed by in vitro analysis of tumor cell lines with forced expression of OLFM4. In an assessment of tissue specimens from 80 patients … postpartum support international birth traumaWebPancreatic ductal adenomcarcinoma (PDAC) is one of the most lethal forms of cancer with a 5-year survival rate of 8%. To determine the composition of different cell types in PDAC, we performed ... postpartum stretch marks treatmentWeb13. maj 2016. · OLFM4 expression is correlated with cancer differentiation, stage, metastasis, and prognosis in a variety of cancers, suggesting its potential clinical value … postpartum support belt in indiaWeb10. jan 2007. · Overexpression of the olfactomedin 4 (OLFM4 GW112,/hGC−1) gene was recently reported to inhibit various apoptotic pathways and promote proliferation of … postpartum stress and anxietyWeb28. sep 2010. · The OLFM4 gene was first identified by virtue of its high expression in colon cancer cells through analysis of Cancer Genome Anatomy Project data from the United States National Cancer Institute. The gene was originally cloned from human haematopoietic myeloid cells and mapped to chromosome 13q14.3 [].It consists of five … postpartum stomach tightening exercises