Web10 set 2024 · Bacterial pneumonia is a persistent cause of mortality and morbidity, and vaccines that target associated pathogens are of great interest. Iwanaga et al. describe a subunit mucosal vaccine that induces protective immunity against heterologous Klebsiella pneumoniae strains. They formulated a vaccine composed of the outer membrane … Web17 feb 2024 · Video abstract of "Considering frailty in SARS-COV-2 vaccine development" [ID 295522]. Abstract: The COVID-19 pandemic has disproportionately impacted frail older adults, especially residents of long-term care (LTC) facilities. This has appropriately led to prioritization of frail older adults and LTC residents, and those who care for them, in ...
Nucleoside-modified mRNA vaccines induce potent T follicular ... - PubMed
Web5 dic 2024 · Individuals who receive a third mRNA vaccine dose show enhanced protection against severe COVID-19, but little is known about the impact of breakthrough infections on memory responses. Here, we examine the memory antibodies that develop after a third or fourth antigenic exposure by Delta or Omicron … Web3 ott 2024 · Shinnakasu et al. show that the glycan engineering immunogens of SARS-CoV-2 spike receptor-binding domain (RBD) elicited higher proportions of the core-RBD-spec chit chats victoria
Multimeric antibodies from antigen-specific human IgM+ memory …
Web4 apr 2016 · Abstract. Traditionally, vaccines have been developed by cultivating infectious agents and isolating the inactivated whole pathogen or some of its purified components. … Web4 giu 2024 · T follicular helper (Tfh) cells are required to develop germinal center (GC) responses and drive immunoglobulin class switch, affinity maturation, and long-term B cell memory. In this study, we characterize a recently developed vaccine platform, nucleoside-modified, purified mRNA encapsulated in lip … Web4 giu 2024 · T follicular helper (Tfh) cells are required to develop germinal center (GC) responses and drive immunoglobulin class switch, affinity maturation, and long-term B … chit chat stroller