WebbTargeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells. Forskningsoutput: Tidskriftsbidrag › Artikel i … Webb8 mars 2016 · Inhibition of AR-V7 transcriptional activity was calculated as the % inhibition of luciferase or PSA mRNA expression in CUDC-101-treated cells compared with vehicle control. Inhibition of flAR activity was calculated as the % inhibition of luciferase or PSA mRNA expression in DHT + CUDC-101-treated cells compared with …
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Webb18 sep. 2024 · Dr. Krebs told the audience that CDK7 inhibition is a promising antitumour strategy. CDK7 is a key kinase, regulating cell division, transcription and nuclear … Webb3 sep. 2014 · Although multiple androgen-receptor variants have been discovered, we focused on AR-V7 because it is the only known androgen-receptor variant encoding a … dennis the menace plant
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Webb22 juni 2024 · Objective The bromodomain and extra-terminal (BET) family of proteins provides a scaffolding platform for the recruitment and tethering of transcription factors … Webb7 apr. 2024 · The heterogeneous response of acute myeloid leukemia (AML) to current anti-leukemic therapies is only partially explained by mutational heterogeneity. We previously identified GPR56 as a surface marker associated with poor outcome across genetic groups, which characterizes two leukemia stem cell (LS … WebbBegäran om inhibition vid överklagande av ett beslut. Hur beslut överklagas och inom vilken tid. Överklagande av avvisningsbeslut. Saken i skatteförfarandet. Särskilt om olika ämnesområden. Alkoholskatt. Bokföring (dispenser) Bouppteckning. Europeiskt … dennis the menace script ss