Ferritin heavy chain 1 fth1
WebNov 3, 2014 · The iron storage protein ferritin is a complex of 24 ferritin light chain (FTL; 134790) and ferritin heavy chain (FTH1) subunits in ratios that vary in different cell … WebNov 28, 2024 · Ferritin, the principal intracellular iron-storage protein localized in the cytoplasm, nucleus, and mitochondria, plays a major role in iron metabolism. ... FTH1 Pseudogenes in Cancer and Cell Metabolism Cells. 2024 Nov 28;9(12):2554. doi: 10.3390/cells9122554. Authors ... Keywords: competing endogenous RNA (ceRNA); …
Ferritin heavy chain 1 fth1
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WebBy performing RNA sequencing analysis, we found that the main iron storage protein ferritin heavy chain 1 (FTH1) is differentially expressed in the rat 6-hydroyxdopamine (6-OHDA) model of PD compared with control rats. Our present work demonstrates that FTH1 is involved in iron accumulation and the ferroptosis pathway in this model. WebStores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). This gene encodes the heavy …
WebFerritin (FTH) is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis by sequestering and storing iron in a non-toxic and bioavailable form (1). The assembled ferritin molecule, often … WebMar 21, 2024 · FTH1 (Ferritin Heavy Chain 1) is a Protein Coding gene. Diseases associated with FTH1 include Hemochromatosis, Type 5 and Iron Overload . Among its …
WebApr 5, 2024 · Ferritin heavy chain (FTH1) exerts significant antigrowth effects in breast cancer cells by inhibiting the expression of c-MYC. Higher CSF Ferritin Heavy-Chain … WebSep 21, 2024 · Ferritin is a widely expressed and highly conserved protein and consists of 2 types of polypeptide chains: ferritin heavy chain and ferritin light chain. Ferritin …
WebNov 16, 2024 · However, piRNA-mediated post-transcriptional gene regulation in human somatic cells is not well understood. We discovered a human piRNA (piR-FTH1) which …
Web1 day ago · Ferritin, which is composed of ferritin heavy chain 1 (FTH1) and ferritin light chain (FTL) [18, 19], is the most important iron storage complex found throughout the … sporcle will smithWebFTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin … sporcle whole worldWebFerritin heavy chain (FTH1) is a 21-kDa subunit of the ferritin complex, known for its role in Iron metabolism. FTH1 contributes to an anti-tumor response in breast cancer patients. Human piRNA (piR-FTH1) has a complementary sequence in the ferritin heavy chain 1 (Fth1) mRNA. Therefore, piR-FTH1 negatively regulates the Fth1 expression at shell shockers cheats on computerWebMedChemExpress offers high purity Ferritin heavy chain/FTH1 Protein, Human with excellent lot-to-lot consistency, superior biological activity and low endotoxin levels. From … sporcle wisdenWebMay 1, 2002 · We have recently reported that heavy chain ferritin (H-ferritin) appears to be another factor released by melanoma cells that may suppress immune responses by … sporcle wipeout 1-100 randomWebAnti-FTH1 antibodies are offered by a number of suppliers. This target gene encodes the protein 'ferritin heavy chain 1' in humans and may also be known as ferritin heavy polypeptide 1, FTH, PIG15, FHC, FTHL6, and apoferritin. Structurally, the protein is reported to be 21.2 kilodaltons in mass. Based on gene name, yeast, canine, porcine ... sporcle wiresporcle wipeout