Crem isoform antibody
WebHere, we tested the role of CREM-IbC-X, a CREM isoform previously isolated from human myocardium (4), in regulating cardiac function in vivo. This isoform belongs to a group of short CREB/CREM mRNAs, including CREB-W (9) and CREMC-X (10), which shows internal translation of small CREB/CREM proteins sharing a high degree of sequence ho- WebSep 10, 2013 · The Crem isoform inducible cAMP early repressor (Icer) is transcribed by the internal promoter P2 as a critical regulator of multiple cellular processes. Here, we describe a novel inducible Crem isoform, small Icer (smIcer), regulated by a newly identified promoter (P6). ChIP revealed binding of CREB to P6 in human and mouse …
Crem isoform antibody
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WebICER (inducible cAMP early repressor) isoforms are transcriptional repressors encoded by the Crem (cAMP responsive element modulator) gene. They were linked to the regulation of a multitude of... WebINS-1 cells were treated for 1 h with 10 μM forskolin (+) or DMSO control (-), then cells were harvested for IP-WB using monoclonal C-terminal anti-CREM 3B5 antibody or monoclonal anti-FLAG M5 ...
WebImmunocytochemistry analysis of CREM in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody ( Product # PA5-115049) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with Alexa Fluor 594 conjugated goat anti-rabbit IgG ... WebSep 29, 2016 · Inducible cAMP early repressor (ICER) has been described as a transcriptional repressor isoform of the cAMP response element modulator (CREM). Here we report that ICER is predominantly expressed in Th17 cells through the IL-6–STAT3 pathway and binds to the Il17a promoter, where it facilitates the accumulation of the …
WebThe transcriptional activation mediated by cAMP-response element (CRE) and transcription factors of the CRE-binding protein (CREB)/CRE modulator (CREM) family represents an important mechanism of cAMP-dependent … WebMar 25, 2024 · The EWSR1::CREM fusion gene, caused by a chromosomal translocation t(10;22)(p11;q12), has been discovered in divergent malignancies, ranging from low-grade to highly malignant cancers. The ...
WebMar 21, 2024 · CREM (CAMP Responsive Element Modulator) is a Protein Coding gene. Diseases associated with CREM include Female Stress Incontinence and Myasthenic …
WebExpression of the CREM isoforms in rat pancreatic islets. A, immunohistochemical localization of CREM protein in pancreatic islets of 8-week-old rats using anti-CREM antibody (dilted to 1:500). Immunocytochemical staining was performed by the avidin-biotin complex method. To ascertain the specificity of the CREM antibody, a testis section was ... edh internationalWebThese peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing … connect feit light bulbWebAntibodies that detect CREM can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. … edh international incWebMar 11, 1999 · Scheme of CREM isoforms 12. CREM proteins incubated with GST–ACT or GST were analysed after GST ‘pull-down’ by western blot using CREM antibodies. … ed hinkle footballed hinzWebOct 8, 2013 · Human cyclic AMP response modulator proteins (CREMs) are encoded by the CREM gene, which generates 30 or more different CREM protein isoforms. They are … edhi online donationWebThis protein interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator)-ACT-mediated gene transcription during … edh irrigation district